STABLIZED MODIFIED RELEASE FOLIC ACID DERIVATIVE COMPOSITION, ITS THERAPEUTIC USE AND METHODS OF MANUFACTURE
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United States of America Patent
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Issued Date -
Jan 29, 2015
app pub date -
Jul 29, 2014
filing date -
Jul 29, 2013
priority date (Note) -
Abandoned
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Abstract
This invention relates to an oral stabilized modified release pharmaceutical dosage form containing L-methylfolate calcium, which is primarily absorbed from proximal small intestine via a saturable human proton-coupled folate transporter (h-PCFT) mediated transport intended as monotherapy for the treatment of patients with MDDs and/or diagnosed with dysthymia, schizophrenia, or degenerative dementia of the Alzheimer type.
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