COMPOSITIONS AND METHODS FOR INDUCING APOPTOSIS
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United States of America Patent
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N/A
Issued Date -
Jan 22, 2015
app pub date -
Aug 10, 2012
filing date -
Aug 12, 2011
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Methods and compositions are provided for generating novel nucleic acid molecules through targeted spliceosome mediated RNA trans-splicing (SMaRT™) that result in expression of a splicing isoform or variant thereof. The methods and compositions are based upon pre-trans-splicing molecules (PTMs) designed to interact with a target pre-mRNA molecule and mediate a trans-splicing reaction generating a novel chimeric RNA molecule encoding a splicing isoform for the treatment of a variety of gene isoform induced diseases such as cancer.
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- 15 United States
- 10 France
- 8 Japan
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- 5 Korea
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Patent Owner(s)
Patent Owner | Address | |
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VIRXSYS CORPORATION | 200 PERRY PARKWAY SUITE 1A GAITHERSBURG MD 20877 |
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Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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McGarrity, Gerard John | Gaithersburg, US | 1 | 0 |
# of filed Patents : 1 Total Citations : 0 |
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