MESENCHYMAL STEM CELLS FOR IN VITRO MODELING AND CELL-BASED THERAPY OF HUMAN DISEASES AND BANKS THEREOF

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United States of America Patent

SERIAL NO

14380174

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Abstract

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A method of qualifying a mesenchymal stem cell (MSC) population is disclosed. The method comprises:

    (a) ex vivo differentiating a population of mesenchymal stem cells originating from the subject towards a first lineage-specific cell, the first lineage-specific cell being associated with a brain disease;(b) ex vivo differentiating a population of mesenchymal stem cells originating from a healthy subject towards the first lineage-specific cell;(c) comparing an effect of the first lineage specific cell derived from the subject with an effect of the first lineage specific cell derived from the healthy subject on a second lineage specific cell associated with the brain disease, wherein a difference in the effect above or below a predetermined level is indicative of a qualification of a mesenchymal stem cell population for cell therapy of said brain disease.

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Patent Owner(s)

Patent OwnerAddress
HENRY FORD HEALTH SYSTEM1 FORD PLACE DETROIT MI 48202

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brodie, Chaya Southfield, US 22 86
Slavin, Shimon Tel-Aviv, IL 46 484

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