Cell Lines That Produce Prostaglandin F2 Alpha (PGF2A) And Uses Thereof
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United States of America Patent
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Issued Date -
Jan 22, 2015
app pub date -
Apr 21, 2010
filing date -
Apr 23, 2009
priority date (Note) -
Abandoned
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Abstract
Cells and cell lines that are genetically modified to express the hCox-2 enzyme, which results in the upregulation of prostaglandin F2 alpha (PGF2a) on the cells have been obtained. Encapsulated cell therapy devices containing such cells or cell lines that are capable of delivering PGF2a, as well as methods of using these devices to deliver PGF2a to the eye and to treat ophthalmic disorders in patients suffering therefrom are also described.
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