TREATMENT FOR HIGH CHOLESTEROL
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United States of America Patent
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Issued Date -
Jan 15, 2015
app pub date -
Mar 8, 2013
filing date -
Mar 9, 2012
priority date (Note) -
Abandoned
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Abstract
The present invention provides a method for treatment of high cholesterol by reducing low density lipoprotein cholesterol (LDL-C) and/or very low density Opoproiein cholesterol (VLDL-C) in subjects In need thereof by administering a compound that inhibits HIF hydroxylase activity. The method is useful, for reducing LDL cholesterol levels and total cholesterol levels even In subjects already undergoing treatment with other cholesterol-lowering medications, for example statins, fibrates, nicotinic acids and bile acid-binding resins, and in patients having chronic kidney disease or end stage renal disease, inter alia.
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