COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS
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United States of America Patent
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Issued Date -
Jan 8, 2015
app pub date -
Aug 28, 2012
filing date -
Sep 1, 2011
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Abandoned
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Abstract
The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.
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