BIOMARKERS OF CANCER

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United States of America Patent

APP PUB NO 20150011411A1
SERIAL NO

14366031

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to identification of a transcriptional signature of RalA and RalB GTPase proteins that is present in human cancer cells, and methods of treating the cancer, methods of diagnosis of the cancer, methods of determining predisposition to the cancer, methods of monitoring progression/regression of the cancer, methods of assessing efficacy of compositions for treating the cancer, methods of screening compositions for activity in modulating biomarker of the cancer, as well as other methods and assay systems based on the signature.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF VIRGINIAVARSITY HALL 136 HOSPITAL DRIVE CHARLOTTESVILLE VA 22903

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baras, Alex Baltimore, US 1 0
Smith, Steven Ann Arbor, US 150 2447
Theodorescu, Dan Englewood, US 16 51

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