METHODS FOR CONTINUOUS ENZYME PRODUCTION USING A FILAMENTOUS FUNGUS WITH INHIBITED GROWTH
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United States of America Patent
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Issued Date -
Jan 1, 2015
app pub date -
Jun 27, 2014
filing date -
Jun 27, 2013
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Abandoned
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Abstract
Methods of continuous production of a product of interest using a filamentous fungus are provided. The fungus is auxotrophic for a nutrient that is required for fungal growth, but not for fungal synthesis of the product of interest. Under growth limiting culture conditions, in which the nutrient is absent from the culture medium, the amount of fungus remains constant or nearly constant and nutrients are not used up for growth but instead are available for synthetic pathways which produce the product of interest.
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