INHIBITOR OF TRPM-4 ION CHANNEL FOR TREATING OR PREVENTING NEURODEGENERATION
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Dec 25, 2014
app pub date -
Dec 21, 2012
filing date -
Dec 29, 2011
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Abstract
The invention relates to a compound which is effective in inhibiting the function of the TRPM4 ion channel and the use of such compound in treating or preventing a neurodegenerative disease, such as Multiple Sclerosis, Parkinson's disease, Alzheimer's disease, or a myotrophic lateral sclerosis, in a subject. The invention also provides a pharmaceutical composition comprising a TRPM4 inhibitory compound. The invention further relates to in vitro methods for identifying pharmaceutically active compounds that are useful for treating or preventing a neurodegenerative disease.
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