BOSENTAN CONTROLLED RELEASE ORAL PREPARATION
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United States of America Patent
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Issued Date -
Dec 25, 2014
app pub date -
May 10, 2013
filing date -
May 11, 2012
priority date (Note) -
Abandoned
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Abstract
Provided are an extended release preparation for oral administration of bosentan including bosentan, a pharmaceutically acceptable salt thereof or a solvate thereof as an active ingredient and a hydrophilic polymer as a sustained release excipient, and a method of manufacturing the same. Accordingly, the number of administrations of the bosentan, a pharmaceutically acceptable salt thereof or a solvate thereof may be reduced, thereby enhancing ease of administration and patient compliance. In addition, the extended release preparation for oral administration of bosentan may be effectively manufactured.
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