METHOD FOR PRODUCTION OF pH STABLE ENVELOPED VIRUSES
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Issued Date -
Dec 25, 2014
app pub date -
Aug 25, 2014
filing date -
Nov 25, 2008
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Abstract
The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.
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