COMPOSITIONS AND METHODS FOR THE RELIEF OF INHIBITION OF ALDEHYDE DECARBONYLASE
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United States of America Patent
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Issued Date -
Dec 18, 2014
app pub date -
Aug 24, 2012
filing date -
Aug 26, 2011
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Abandoned
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Abstract
The present invention is related to compositions and methods for enhanced synthesis of hydrocarbons, particularly, but not limited to, alkanes. The invention, in one embodiment, utilizes the co-expression of a hydrogen peroxide metabolizing enzyme in the presence of an aldehyde decarbonylase enzyme to relieve hydrogen peroxide inhibition of the aldehyde decarbonylase enzyme by hydrogen peroxide. In a preferred embodiment a catalase-aldehyde decarbonylase expression construct and fusion peptide is used. The present invention also relates to microorganisms engineered to express said enzymes and to produce hydrocarbon molecules.
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