Angiogenin for treatment of glaucoma
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United States of America Patent
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Jan 2, 2018
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app pub date -
Feb 27, 2012
filing date -
Oct 6, 2011
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Abstract
The present invention provides a pharmaceutical composition for the prevention or treatment of glaucoma, wherein the pharmaceutical composition includes angiogenin or a fragment thereof as an active ingredient. Angiogenin or a fragment thereof according to the present invention activates aqueous humor outflow due to NO generation increase, Schlemm's canal expansion, and intercellular interval widening, thereby reducing intraocular pressure. Accordingly, angiogenin and a fragment may be useful for the prevention and treatment of glaucoma.
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