dsRNA/DNA Hybrid Genome Replication Intermediate Of Metakaryotic Stem Cells
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United States of America Patent
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Issued Date -
Dec 18, 2014
app pub date -
Jun 1, 2012
filing date -
Jun 2, 2011
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Abstract
The invention provides methods of identifying metakaryotic stem cells, as well as methods of identifying agents that selectively modulate the growth, migration, replication, and/or survival of these cells by detecting an intermediate dsRNA/DNA duplex genome. Also provided are diagnostic, prognostic, and treatment methods for disorders, such as atherosclerosis, restenosis, and benign or malignant tumors.
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