IN VIVO LABEL-FREE HISTOLOGY BY PHOTOACOUSTIC MICROSCOPY OF CELL NUCLEI
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United States of America Patent
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Issued Date -
Dec 4, 2014
app pub date -
Dec 7, 2012
filing date -
Dec 8, 2011
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Abstract
The present disclosure is directed to methods of non-invasively imaging cell nuclei. More particularly, the present disclosure is directed to methods of imaging cell nuclei in vivo using ultraviolet photoacoustic microscopy (UV-PAM), in which ultraviolet light is used to excite unlabeled DNA and RNA in cell nuclei to produce photoacoustic waves.
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