MATERIALS AND METHODS FOR TREATMENT OF LIVER CANCER
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United States of America Patent
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Issued Date -
Dec 4, 2014
app pub date -
May 30, 2014
filing date -
May 30, 2013
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Abstract
Granulin-epithelin precursor (GEP), a pluripotent growth factor, is a hepatic oncofetal protein defining a cancer stem cell (CSC) population in liver cancer. The present invention provides the use of GEP inhibitors (including anti-GEP antibody) for inhibiting immune evasion by liver cancer cells and for eliminating liver cancer stem cells.
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