INHIBITION OF VIRAL GENE EXPRESSION
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United States of America Patent
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Issued Date -
Nov 27, 2014
app pub date -
Oct 26, 2012
filing date -
Oct 28, 2011
priority date (Note) -
Abandoned
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Abstract
This invention relates to modified short interfering RNA (siRNA) nucleic acid molecules, particularly siRNA's which have been modified by the addition of a 2-0-guanidinopropyl (GP) modified nucleoside. In particular the invention relates to modified siRNAs which are capable of silencing target sequences, methods of treating and preventing infection by using the siRNAs, medicaments containing the siRNAs and use of the siRNAs.
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