NEW TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF
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Issued Date -
Nov 27, 2014
app pub date -
Jun 25, 2012
filing date -
Jun 27, 2011
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Abstract
Methods are described for using genes crucial in TH17 differentiation, IL-12Rbeta 1/IL-23R, CCR6, BATF, AHR, STAT3 and IRF4 as new markers for rosacea. Also described, are methods of their use to diagnose rosacea, to screen inhibitors of Th17 differentiation. In particular, method are described for inhibiting at least one of these genes and using the screened inhibitors in rosacea treatment.
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