REPROGRAMMING IMMORTALIZED B CELLS
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United States of America Patent
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May 21, 2014
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Aug 4, 2010
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Abstract
Methods and composition for providing induced pluripotent stem (iPS) cells are provided. For example, in certain aspects methods including reprogramming B lymphocytes transformed by episomal vectors such as Epstein-Barr virus-based vectors are described. Furthermore, the invention provides induced pluripotent stem cells essentially free of exogenous elements and having B cell immunoglobin variable region rearrangement.
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