Orally dispersible tablet containing compacted sildenafil base

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United States of America Patent

PATENT NO 9301959
APP PUB NO 20140343072A1
SERIAL NO

14452209

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Abstract

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The invention relates to a process for the preparation of a pharmaceutical intermediate, comprising the steps of (i) mixing (a-i) sildenafil base, (b-i) wicking agent, (c-i) disintegrant, (d-i) optionally glidant; (ii) compacting the mixture; and (iii) milling the compacted material; and to an intermediate obtainable by that process. In addition, the invention relates to a process for the preparation of an orally dispersible tablet (hereinafter also referred to as an “orodispersible tablet”) comprising the intermediate of the invention, and to orodispersible tablets obtainable by that process.

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Patent Owner(s)

Patent OwnerAddress
RATIOPHARM GMBH89079 ULM

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Scheiwe, Max-Werner Maulburg, DE 8 54
Swatschek, Dieter Blaubeuren, DE 6 17
Winter, Sven Neubeckum, DE 10 69

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