FORMULATIONS OF VITAMIN K ANALOGS FOR TOPICAL USE
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United States of America Patent
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Issued Date -
Nov 13, 2014
app pub date -
Jul 21, 2014
filing date -
Mar 13, 2008
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Abandoned
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Abstract
The present invention provides topical formulations containing a vitamin K analog, e.g., menadione, that deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin in a vehicle which is stable, non-irritating, non-drying and cosmetically acceptable. These topical formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly, dermatological conditions resulting from anti-EGFR therapies.
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