Protein Carrier-Linked Prodrugs
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United States of America Patent
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Issued Date -
Oct 30, 2014
app pub date -
Aug 10, 2012
filing date -
Aug 12, 2011
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Abstract
The present invention relates to water-soluble protein carrier-linked prodrugs wherein the protein carrier comprises an amino acid sequence consisting of at least 100 amino acid residues forming random coil conformation and comprising alanine, serine and proline residues. It further relates to pharmaceutical compositions comprising said water-soluble protein carrier-linked prodrugs, their use as a medicament as well as methods of treatment and administration.
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