EUKARYOTIC ORGANISMS AND METHODS FOR INCREASING THE AVAILABILITY OF CYTOSOLIC ACETYL-COA, AND FOR THE PRODUCING 1,3-BUTANEDIOL

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United States of America Patent

APP PUB NO 20140322779A1
SERIAL NO

14357497

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Abstract

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Provided herein are non-naturally occurring eukaryotic organisms that can be engineered to produce and increase the availability of cytosolic acetyl-CoA. Also provided herein are non-naturally occurring eukaryotic organisms having a 1,3-butanediol (1,3-BDO) pathway, and methods of using such organisms to produce 1,3-BDO.

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GENOMATICA INC4757 NEXUS CENTER DRIVE SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burgard, Anthony P Bellefonte, US 199 3095
Burk, Mark J San Diego, US 199 2040
Li, Jingyi San Diego, US 61 82
Osterhout, Robin E San Diego, US 156 1473
Pharkya, Priti San Diego, US 156 1697

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