CTC BIOMARKER ASSAY TO COMBAT BREAST CANCER BRAIN METASTASIS

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United States of America Patent

APP PUB NO 20140322356A1
SERIAL NO

14361248

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Embodiments of the present invention concern methods related to treating, prognosticating and/or diagnosing at least brain metastatic breast cancer. Embodiments of the methods include characterizing circulating tumor cells for the presence or absence of EpCAM and, upon identification of EpCAM negative cells and identification of the status of other markers (such as heparanase and/or Notch1, for example), treating the individual based on the determination of the characterization.

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Patent Owner(s)

Patent OwnerAddress
BAYLOR COLLEGE OF MEDICINEONE BAYLOR PLAZA HOUSTON TX 77030

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Marchetti, Dario Seabrook, US 4 4
Ridgway, Lon Houston, US 1 2
Zhang, Lixin Houston, US 168 2390

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