METHOD TO GENERATE DOPAMINERGIC NEURONS FROM MOUSE AND HUMAN CELLS
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United States of America Patent
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Issued Date -
Oct 23, 2014
app pub date -
Dec 13, 2011
filing date -
Dec 13, 2010
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Abandoned
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Abstract
The present invention relates to a method for reprogramming a differentiated non neuronal cell into a dopaminergic neuron comprising the step of inducing the expression in the differentiated non neuronal cell of at least the protein encoded by the Mash1 human gene or orthologues thereof and the protein encoded by the Nurr1 human gene or orthologues thereof, expression vectors, reprogrammed dopaminergic neuron and uses thereof.
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