ANTI-CXCR4 ANTIBODIES AND METHODS OF USE
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United States of America Patent
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Issued Date -
Oct 23, 2014
app pub date -
Jul 19, 2012
filing date -
Jul 20, 2011
priority date (Note) -
Abandoned
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Abstract
The disclosure relates to antibodies or antigen binding fragments that specifically bind to CXCR4 and inhibit the biological activity of CXCR4 and uses of such agents. More specifically the disclosure relates to fully human antibodies or antigen binding fragments directed to CXCR4 that specifically bind to CXCR4 and uses of these antibodies. Aspects of the disclosure also relate to hybridomas or other cell lines expressing such antibodies. The disclosed antibodies (including antigen binding fragments) are useful as diagnostics and for the treatment of diseases associated with the activity and/or expression of CXCR4.
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