USE OF ORGANIC SOLVENT NANOFILTRATION AND LIQUID-LIQUID CHROMATOGRAPHY FOR THE RECOVERY OF PHARMACEUTICAL PRODUCTS
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United States of America Patent
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Issued Date -
Oct 23, 2014
app pub date -
Nov 20, 2012
filing date -
Nov 22, 2011
priority date (Note) -
Abandoned
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Abstract
A process for separating a compound from solution in organic solvent by a chromatographic process, in particular liquid-liquid chromatography, in which prior to the chromatographic process the composition of the solution is changed by means of a process of organic solvent nanofiltration for a solvent exchange. Additionally or alternatively subsequent to the chromatographic process the output from the chromatographic process is subjected to a process of organic solvent nanofiltration to remove residual target compound and/or impurities in the output for solvent recovery.
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