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Country	kind	publication No.	Filing Date	Type	Sub-Type
US	B2	US9116157	Nov 04, 2011	Patent	Grant
Type : Patent Sub-Type : Grant
GRANTED PATENT AS SECOND PUBLICATION		Ice-cleaved alpha-synuclein as a biomarker		Aug 25, 2015
WO	A1	WO2012061786	Nov 04, 2011	Patent	Application
Type : Patent Sub-Type : Application
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT		ICE CLEAVED ALPHA-SYNUCLEIN A BIOMARKER		May 10, 2012
WO	A2	WO2012061785	Nov 04, 2011	Patent	Application
Type : Patent Sub-Type : Application
INTERNATIONAL APPLICATION PUBLISHED WITHOUT INTERNATIONAL SEARCH REPORT or INTERNATIONAL APPLICATION PUBLISHED WITH DECLARATION UNDER ARTICLE 17 (2) (A)		ICE INHIBITING COMPOUNDS AND USES THEREOF		May 10, 2012
JP	B2	JP5980790	Nov 04, 2011	Patent	Grant
Type : Patent Sub-Type : Grant
PUBLISHED GRANTED PATENT (SECOND LEVEL)		バイオマーカーとしての、ＩＣＥ切断されたアルファ−シヌクレイン		Aug 31, 2016
EP	A1	EP2635907	Nov 04, 2011	Patent	Application
Type : Patent Sub-Type : Application
APPLICATION PUBLISHED WITH SEARCH REPORT		ICE CLEAVED ALPHA-SYNUCLEIN A BIOMARKER		Sep 11, 2013
EP	A2	EP2635906	Nov 04, 2011	Patent	Application
Type : Patent Sub-Type : Application
APPLICATION PUBLISHED WITHOUT SEARCH REPORT		ICE INHIBITING COMPOUNDS AND USES THEREOF		Sep 11, 2013
JP	B2	JP6006908	Nov 04, 2011	Patent	Grant
Type : Patent Sub-Type : Grant
PUBLISHED GRANTED PATENT (SECOND LEVEL)		ＩＣＥ阻害化合物およびその使用		Oct 12, 2016
US	A1	US20160143985	Jun 25, 2015	Patent	Application
Type : Patent Sub-Type : Application
FIRST PUBLISHED PATENT APPLICATION		ICE-CLEAVED ALPHA-SYNUCLEIN AS A BIOMARKER		May 26, 2016

• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
BRANDEIS UNIVERSITY	415 SOUTH STREET WALTHAM MA 02454

International Classification(s)

• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
• C12Q:MEASURING OR TESTING PROCESSES INVOLVING ENZYMES O....
• G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....

• 2011 Application Filing Year
• A61K Class
• 10915 Applications Filed
• 8360 Patents Issued To-Date
• 76.60 % Issued To-Date

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Hoang, Quyen	Carmel, US	5	11
# of filed Patents : 5 Total Citations : 11
Petsko, Gregory A	Belmont, US	10	27
# of filed Patents : 10 Total Citations : 27
Ringe, Dagmar	Cambridge, US	12	31
# of filed Patents : 12 Total Citations : 31

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Patent Citation Ranking

• 1 Citation Count
• A61K Class

• 21.20 % this patent is cited more than
• 11 Age

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Fee	Large entity fee	small entity fee	micro entity fee	due date
11.5 Year Payment	$7400.00	$3700.00	$1850.00	Apr 16, 2026

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

Full Text

US Patent Application No: 2018/0094,029

METHODS OF TREATING OPHTHALMIC DISEASES USING NPR-B AGONISTS

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Abstract

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Disclosed are novel compounds having NPR-B agonistic activity. Preferred compounds are linear peptides containing 8-13 conventional or non-conventional L- or D-amino acid residues connected to one another via peptide bonds.

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Description

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Claims

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