PROCESS FOR PRODUCING CELLULASES USING A FILAMENTOUS FUNGUS SUITABLE FOR A FERMENTER, HAVING A LOW VOLUMETRIC OXYGEN TRANSFER COEFFICIENT KLA
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United States of America Patent
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Oct 9, 2014
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Aug 2, 2012
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Aug 19, 2011
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Abstract
The present invention concerns a process for the production of cellulases using a strain of a filamentous fungus in a stirred, aerated bioreactor, comprising at least two growth steps:
- the first growth step in the presence of at least one carbonaceous growth substrate in batch phase with a concentration of carbonaceous growth substrate in the range 10 to 80 g/L;a second step for growth and production in the presence of at least one inducer carbonaceous substrate in fed batch phase in the presence of a limiting flow of carbon source in the range 50 to 140 mg per gram of cells per hour.
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