Engineered E2 For Increasing The Content Of Free LYS11-Linked Ubiquitin
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United States of America Patent
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Issued Date -
Oct 9, 2014
app pub date -
May 13, 2014
filing date -
May 7, 2010
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Abandoned
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Abstract
The invention provides a chimeric E2 enzyme comprising a Ubc domain fused to a heterologous ubiquitin binding domain (UBD). The chimeric enzymes of the invention may be useful in producing elevated levels of free polyubiquitin.
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