DRUG SCREENING METHOD AND USES THEREOF
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United States of America Patent
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Oct 2, 2014
app pub date -
Nov 9, 2012
filing date -
Nov 11, 2011
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Abstract
Described herein are methods of screening drugs in a non-human animal using high resolution technology leading to generation of pharmacomaps. Further described herein are methods of predicting the therapeutic benefit and/or toxicity of drug candidate compounds. In specific embodiments, provided herein are methods of predicting the clinical effects of a test drug based on comparison of the pharmacomap of the test drug to the pharmacomap of one or more reference drugs with known clinical outcomes.
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