NICLOSAMIDE FOR THE TREATMENT OF CANCER METASTASIS

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United States of America Patent

APP PUB NO 20140294957A1
SERIAL NO

14112521

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to niclosamide and derivates thereof, which effectively inhibit transcription of the S100A4 gene, resulting in inhibition and/or reduction of S100A4-induced cell motility, invasiveness, metastasis and proliferation of human cancer cells.

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Patent Owner(s)

Patent OwnerAddress
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICESNATIONAL INSTITUTES OF HEALTH 6011 EXECUTIVE BOULEVARD SUITE 325 MSC 7660 BETHESDA MD 20892-7660

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sack, Ulrike Berlin, DE 16 55
Schlag, Peter M Berlin, DE 4 10
Scudiero, Dominic Frederick, US 4 15
Shoemaker, Robert Boyds, US 2 9
Stein, Ulrike Panketal, DE 11 20
Walther, Wolfgang Panketal, DE 17 55

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