SYSTEM AND METHOD TO IDENTIFY DYSREGULATED PATHWAYS AND RELATED INTERACTIONS
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United States of America Patent
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Issued Date -
Sep 25, 2014
app pub date -
Mar 17, 2014
filing date -
Mar 15, 2013
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Abandoned
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Abstract
A method can compute a cooperation profile for at least two genes according to a gene expression data set for each of a plurality of genes, the cooperation profile representing cooperation interactions dysregulated in at least one disease. A competition profile for genes according to the gene expression data set, the competition profile representing a competitive interaction between the genes. A redundancy profile can be computed for the at least two genes according to the gene expression data set for each of the genes, the redundancy profile representing a maximum expression for the genes. A dependency profile for the at least two genes can be according to the gene expression data set for each of the genes, the dependency profile representing a minimum expression for the genes. Some of the computed profiles can be analyzed to identify dysregulated interactions between gene pairs and/or dysregulated pathways.
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