L-GLUCOSE PRODUCTION FROM L-GLUSOSE/L-MANNOSE MIXTURES USING SIMULATED MOVING BED SEPARATION
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United States of America Patent
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Issued Date -
Sep 18, 2014
app pub date -
Mar 14, 2013
filing date -
Mar 14, 2013
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Abandoned
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Abstract
Disclosed is a process for the production of L-glucose from a mixture of L-mannose and L-glucose to provide a high purity L-glucose product. More particularly, the invention relates to a process for the isomerization of mixtures of L-mannose and L-glucose to favor the epimerization or transformation of the L-mannose into L-glucose combined with the selective removal of impurities and the selective separation of L-glucose by a multi-stage simulated moving bed SMB separation process integrating ion exclusion and isomer separation. The process is useful for providing a simplified and economic continuous processing route to providing pure L-glucose from mixtures of L-glucose and L-mannose in the presence of inorganic and organic salts and other sugars such as L-arabinose. L-glucose is useful as a sweetener, a laxative and as a therapeutic agent.
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