Methods and Apparatus for Decomposing Tandem Mass Spectra Generated by All-Ions Fragmentation
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United States of America Patent
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Issued Date -
Sep 11, 2014
app pub date -
Mar 5, 2013
filing date -
Mar 5, 2013
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Abstract
A method for tandem mass spectrometry of a plurality of eluting compounds comprises: (a) performing, during a time period, the steps of: ionizing the plurality of eluting compounds to generate a plurality of precursor ion species; introducing the plurality of precursor ions into a fragmentation cell operated at constant fragmentation energy so as to generate a plurality of product-ion species from at least a portion of the precursor ion species; and generating a mass spectrum of the plurality of product-ion species; and (b) recognizing matches between certain of the product ion species generated during the time period based on correlations between elution profiles of the product ion species.
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