STACKED PLANAR SHEET TISSUE ENGINEERING SCAFFOLDS WITH 3D STRUCTURAL ORDER
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United States of America Patent
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Aug 28, 2014
app pub date -
Feb 28, 2013
filing date -
Feb 28, 2013
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Abstract
A three-dimensional tissue engineering scaffold device and related methods are disclosed herein. The tissue engineering scaffold includes a plurality of polymers sheets. Each polymer sheet includes a plurality of micro-scale pores defined through the polymer sheet. The polymer sheets of the tissue engineering scaffold are aligned and stacked such that some of the pores of neighboring sheets are offset along at least one axis of the pores. The offset pores create features within the tissue engineering scaffold. In some implementations, the tissue engineering scaffold device is seeded with cells. In certain implementations, the tissue engineering scaffold is either implanted into a patient or used to grow functional tissue ex vivo.
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