ANTIBODIES AND ANTIBODY FRAGMENTS TARGETING SIRP-ALPHA AND THEIR USE IN TREATING HEMATOLOGIC CANCERS

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United States of America Patent

APP PUB NO 20140242095A1
SERIAL NO

14352265

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to modulating the SIRPα—CD47 interaction in order to treat hematological cancer and compounds therefor. In particular, there is also provided SIRPα antibodies and antibody fragments, preferably used for treating hematological cancer.

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Patent Owner(s)

Patent OwnerAddress
THE HOSPITAL FOR SICK CHILDREN555 UNIVERSITY AVENUE TORONTO ONTARIO M5G 1X8

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Danska, Jayne S Toronto, CA 2 36
Dick, John Toronto, CA 20 220
Sidhu, Sachdev Toronto, CA 38 252
Uppalapati, Maruti Toronto, CA 10 54
Wang, Jean C Y Toronto, CA 2 36

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