NKP46-MEDIATED NK CELL TUNING
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United States of America Patent
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Issued Date -
Aug 21, 2014
app pub date -
Jun 21, 2012
filing date -
Jun 21, 2011
priority date (Note) -
Abandoned
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Abstract
The present invention relates to compounds (e.g. antibodies) that specifically bind and inhibit NKp46. Such compounds are capable, when administered to a mammal, capable of increasing the frequency of reactive and/or active NK cells. The invention also relates to pharmaceutical composition and methods of using the antibodies and compositions to treat or prevent diseases, e.g. cancer, infection, autoimmune diseases, inflammatory diseases and the like.
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