COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS
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United States of America Patent
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Issued Date -
Aug 21, 2014
app pub date -
May 5, 2014
filing date -
Sep 30, 2008
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We have discovered that p63 inhibition results in increased cellular proliferation. We have also performed a screen for agents capable of increasing cellular proliferation, (e.g., of stem cells such as skin-derived precursors (SKPs)). The invention therefore invention provides compositions, methods, and kits for increasing proliferation of cells, using compounds that decrease p63 expression or activity or using the compounds described herein. The invention also features methods of using these compounds for increasing hair growth, improving skin health, or promoting skin repair in a subject.
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