5,7-SUBSTITUTED-IMIDAZO[1,2-C]PYRIMIDINES
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United States of America Patent
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Issued Date -
Aug 14, 2014
app pub date -
Oct 9, 2012
filing date -
Oct 12, 2011
priority date (Note) -
Abandoned
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Abstract
Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
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