AMINO ACID-CONJUGATED CYANOACRYLATE POLYMER PARTICLES

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United States of America Patent

SERIAL NO

14261813

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are cyanoacrylate polymer particles which comprise an amino acid(s) and have an average particle diameter of less than 1000 nm. The amino acid-containing particles according to the present invention can kill cancer cells by inducing apoptosis-like cell death. The particles have an especially high affinity for cell lines derived from lymphomas such as T-cell lymphoma and B-cell lymphoma. The particles can also exhibit an antiproliferative effect against some kinds of pancreatic cancer-derived cell lines. Therefore, the particles according to the present invention are useful for prevention and/or treatment of cancers.

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Patent Owner(s)

Patent OwnerAddress
PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITYKANAGAWA KANAGAWA

International Classification(s)

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  • 2014 Application Filing Year
  • C08G Class
  • 2377 Applications Filed
  • 2099 Patents Issued To-Date
  • 88.31 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201420152016201720182019202020212022202320240255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
ENDO, Itaru Yokohama-shi, JP 15 301
SHIROTAKE, Shoichi Yokohama-shi, JP 7 17
YOKOTA, Shumpei Yokohama-shi, JP 9 242
YOSHIDA, Atsushi Yokohama-shi, JP 326 4180

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  • C08G Class
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  • 11 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1406831194019963112501 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +050100150200250300350400450500550600650700750

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