Methods and Compositions for Increasing Protein Production
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United States of America Patent
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Issued Date -
Aug 7, 2014
app pub date -
Feb 26, 2014
filing date -
May 5, 2009
priority date (Note) -
Abandoned
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Abstract
The disclosure provides methods and materials for increasing the expression of a protein of interest such as an antibody by a cell. ABC50 expression or activity is increased which increases expression of the protein or antibody of interest. The disclosure also provides methods and materials for increasing the sensitivity of a cell to an endoplasmic reticulum stress agent such as Econozole by decreasing the level of ABC50.
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