COMPUTER-IMPLEMENTED SYSTEM AND METHOD FOR THE PREDICTION OF CANCER RESPONSE TO GENOTOXIC CHEMOTHERAPY AND PERSONALISED NEOADJUVANT TREATMENTS (PCCP)

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United States of America Patent

APP PUB NO 20140221232A1
SERIAL NO

14129727

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for predicting an individual's response to a treatment for cancer, the method comprising a step of assaying a biological sample from the individual to determine the abundance of a panel of two or more bio-markers comprising pro-apoptotic and/or anti-apoptotic biomarkers; inputting the abundance value for the two bio-markers into a computational model of a mitochondrial apoptosis pathway; and processing said abundance values using said computational model to provide a value to predict the individual's response to treatment.

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Patent Owner(s)

Patent OwnerAddress
ROYAL COLLEGE OF SURGEONS IN IRELAND123 ST STEPHENS GREEN DUBLIN D2

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Huber, Heinrich Kessel-Lo, BE 6 10
Prehn, Jochen Dublin, IE 4 0
Rehm, Markus Dublin, IE 21 181

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