OPTICAL CONTROL OF PROTEIN ACTIVITY AND LOCALIZATION BY FUSION TO PHOTOCHROMIC PROTEIN DOMAINS
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Issued Date -
Aug 7, 2014
app pub date -
Apr 11, 2014
filing date -
Mar 22, 2012
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Abstract
Engineered fusion proteins comprising photochromic protein domains are disclosed. In particular, the inventors have constructed fusion proteins containing photoswitchable photochromic fluorescent protein domains linked to selected proteins and shown that such fusion proteins can be used to control the activity or localization of selected proteins with light.
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