ECTOCORNEA-LIKE SHEET AND METHOD OF CONSTRUCTING THE SAME

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United States of America Patent

SERIAL NO

14175369

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Abstract

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It is intended to provide a transplantation material applicable to ocular surface diseases with a need for ectocornea transplantation (i.e., an ectocornea-like sheet). Oral mucosal epithelial cells are inoculated onto an amnion and then cultured in the coexistence of supporter cells. When a layered structure of the oral mucosal epithelial cells is formed, the outermost layer is brought into contact with air, thereby inducing differentiation. Thus, an ectocornea-like sheet having an oral mucosal epithelial cell layer on the amnion is obtained.

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Patent Owner(s)

Patent OwnerAddress
FOUNDATION FOR BIOMEDICAL RESEARCH AND INNOVATIONKOBE HYOGO 650-0047

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kinoshita, Shigeru Osaka, JP 95 409
Nakamura, Takahiro Kyoto, JP 195 3533

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