CERAMIDE ANIONIC LIPOSOME COMPOSITIONS
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United States of America Patent
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Issued Date -
Jul 31, 2014
app pub date -
Apr 3, 2014
filing date -
May 10, 2011
priority date (Note) -
Abandoned
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Abstract
Described herein are pharmaceutical compositions according to aspects of the present invention which include one or more hydrophilic antineoplastic chemotherapeutics, such as vinca alkyloid antineoplastic chemotherapeutics, encapsulated in ceramide anionic liposomes. Methods of treatment of a subject having cancer using the pharmaceutical compositions are described, along with methods of making ceramide anionic liposomes which encapsulate one or more hydrophilic antineoplastic chemotherapeutics in the aqueous interior of the ceramide anionic liposomes.
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