METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF MACROMOLECULES

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United States of America Patent

APP PUB NO 20140212421A1
SERIAL NO

14190788

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Abstract

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The invention provides compositions and methods that enhance the delivery of large macromolecules (i.e., greater than 10 kDa), such as antigen-binding polypeptides, across tight junctions. Such methods and compositions are particularly useful for delivering therapeutic antigen-binding polypeptides to the CNS, via intranasal administration, for the treatment of neurological disorders.

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Patent Owner(s)

Patent OwnerAddress
ESBATECH AN ALCON BIOMEDICAL RESEARCH UNIT LLC8952 SCHLIEREN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Furrer, Esther Forch, CH 2 8
Hulmann-Cottier, Valerie Zurich, CH 9 22
Urech, David Jona, CH 67 259

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