LPA2 RECEPTOR-SPECIFIC BENZOIC ACID DERIVATIVES

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United States of America Patent

APP PUB NO 20140206714A1
SERIAL NO

14222473

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed are compounds effective for inhibiting cellular apoptosis and for protecting cells and tissues from the apoptotic effects of chemotherapeutic agents and/or ionizing radiation. Compounds of the invention act as agonists of the LPA2 receptor. Compounds of the invention comprise non-lipid benzoic acid derivatives. Further disclosed is a pharmacophore of LPA2 receptor.

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Patent Owner(s)

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UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONKNOXVILLE TN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fells, James Memphis, US 8 0
Miller, Duane Germantown, US 12 11
Patil, Renukadevi Germantown, US 8 30
Tigyi, Gabor Memphis, US 15 73

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