COMPOUNDS AND COMPOSITIONS AS PDGFR KINASE INHIBITORS

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United States of America Patent

SERIAL NO

14241886

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Abstract

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The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of PDGFR (PDGFRα, PDGFRβ) kinases or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.

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Patent Owner(s)

Patent OwnerAddress
NOVARTIS PHARMACEUTICALS UK LIMITEDFRIMLEY BUSINESS PARK FRIMLEY CAMBERLEY SURREY GU16 7SR

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Berman, Ashley Mitchell San Diego, US 1 0
Furminger, Vikki Camberley Surrey, GB 10 50
Gibney, Michael San Diego, US 4 44
Lewis, Sarah Horsham, GB 9 34
Li, Xiaolin Alameda, US 141 1247
Liang, Fang Encinitas, US 21 58
Loren, Jon San Diego, US 22 379
Molteni, Valentina San Diego, US 56 467
Shaw, Duncan Horsham, GB 19 52
Yeh, Vince San Diego, US 22 114

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