GENE EXPRESSION MARKERS FOR PREDICTION OF PATIENT RESPONSE TO CHEMOTHERAPY

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United States of America Patent

APP PUB NO 20140206545A1
SERIAL NO

14132679

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to gene sets useful in assessing prognosis and/or predicting the response of cancer, e.g. colorectal cancer to chemotherapy. In addition, the invention relates to a clinically validated cancer test, e.g. colorectal test, for assessment of prognosis and/or prediction of patient response to chemotherapy, using expression analysis. The present invention accommodates the use of archived paraffin embedded biopsy material for assay of all markers in the relevant gene sets and therefore is compatible with the most widely available type of biopsy material.

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Patent Owner(s)

Patent OwnerAddress
GENOMIC HEALTH INC301 PENOBSCOT DRIVE REDWOOD CITY CA 94063
NSABP FOUNDATION INCFOUR ALLEGHENY CENTER 5TH FLOOR PITTSBURGH PA 15212

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
BAKER, Joffre B Montara, US 80 1605
CLARK-LANGONE, Kim M Redwood City, US 1 2
COWENS, Wayne Tiburon, US 24 339
HACKETT, James San Diego, US 22 329
PAIK, Soonmyung Pittsburgh, US 36 780
WATSON, Drew Los Altos, US 18 291

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